Efeito da associação da terapia com laser de baixa potência e alta frequência no processo de cicatrização em feridas cutâneas de ratos

Abstract

Introduction: Ulcers represent an important intercurrence of human health judged by the social and economic aspect due to the long time and difficulty in cicatrization. Objective: To evaluate the effect of the 660nm low power laser associated with high frequency therapy on the healing process and tissue repair in cutaneous ulcers. Materials and methods: The research was carried out in the laboratories of the Federal University of the West of Pará, State University of Pará and Esperança Institute of Higher Education in Santarém. The research period was between November and November 2018. Twenty Wistar rats were divided into 4 groups, each consisting of 5 animals each. Group GC (Control Group - received the lesion, however, without any treatment). Group GL (Laser therapy group - received the lesion and was treated with Laser therapy). Group GAL (High frequency group - received the lesion and was treated with High frequency). Group GL + Al (Group Lasertherapy and high frequency - received the lesion and was treated with laser therapy and associated high frequency). After the occurrence of the lesion, the animals started pre-determined daily therapy sessions for each group, established randomly, for ten consecutive days. Euthanasia of the animals occurred on the 11th day after the initial lesion. Results: At the end of treatment it was possible to observe significantly (p <0.01) lower lesion area in GL compared to the LAG group. It was also possible to observe a significant reduction (p <0.05) in GALxGL compared to LAG. There was no significant difference between the types of collagens in each group analyzed (p> 0.05). Conclusion: The low power laser is able to efficiently modulate the process of repairing skin wounds based on macroscopic and microscopic aspects. The high frequency generator is not able to efficiently modulate the skin wounds repair process based on macroscopic aspects, however it improves the repair process on skin wounds based on microscopic aspects. The low power laser associated with the generator of high frequency present good results in the process of tissue repair.